Michelangelo: Not Lying Down, the JAMA Hidden Brain of 1990, and the Self-Portrait as a Flayed Skin

Michelangelo biography complete guide DeckArts Berlin JAMA brain not lying down flayed skin

Last updated: · By Stanislav Arnautov · Berlin

Quick answer

Michelangelo Buonarroti (6 March 1475 – 18 February 1564): born Caprese; NOT painted the Sistine Chapel ceiling lying down (he wrote a sonnet about it: “my brush, above me all the time, drips down”); the hidden brain in God’s mantle was confirmed by a physician in JAMA in October 1990; the 1.2 cm gap between God’s and Adam’s fingers is deliberate; he placed his own face on the flayed skin of St Bartholomew in the Last Judgment. He died aged 88. DeckArts Creation of Adam single (~$140) and Last Judgment triptych (~$310).

Michelangelo di Lodovico Buonarroti Simoni (6 March 1475 – 18 February 1564) is the most celebrated sculptor, painter, architect, and poet of the Italian Renaissance and the artist whose biography contains the greatest number of permanent biographical revelations: the ceiling was not painted lying down (documented by his own sonnet); the hidden brain in God’s mantle was identified by a physician in the Journal of the American Medical Association in October 1990; the 1.2 cm gap between God’s and Adam’s fingers is the composition’s most specific deliberate event; and his own face appears on the flayed skin of Saint Bartholomew in the Last Judgment. He conducted illegal dissections of corpses from 1493 onward for anatomical study. He lived to 88 years old — the longest life of any major artist of the Italian Renaissance. At the Musei Vaticani, Rome (Sistine Chapel); Uffizi Gallery, Florence. DeckArts Berlin from ~$140.

Early Life: Caprese, Florence, and the Medici

Michelangelo was born on 6 March 1475 in Caprese (now Caprese Michelangelo, in the province of Arezzo, Tuscany), where his father Ludovico di Leonardo Buonarroti Simoni was serving as the Florentine government’s podestà (governor) for the six-month term. The family returned to Florence shortly after Michelangelo’s birth; he grew up in Florence in the household of a stonecutter in the Settignano hills, where, according to his biographer Giorgio Vasari, he later claimed that “with the milk of my nurse I sucked in the chisels and hammers with which I make my figures.”

His mother Francesca di Neri del Miniato di Siena died in 1481, when Michelangelo was six years old. He was effectively raised by his father and by the stonecutter’s family in Settignano. His father Ludovico, despite his own minor nobility status, initially objected to his son entering an artisan’s profession (painting was considered a manual craft, not an intellectual discipline, in 15th-century Florence). Vasari records that Michelangelo received beatings from his father for his determination to draw and paint. The father eventually relented.

In 1488, at approximately age 13, Michelangelo was apprenticed to the Florentine painter Domenico Ghirlandaio, one of the leading fresco painters in Florence. His time in the Ghirlandaio workshop lasted approximately one year; he left or was expelled (the accounts differ) in approximately 1489. In 1489–1490, he was admitted to the sculpture garden of Lorenzo de’ Medici in the gardens of San Marco, where he studied ancient sculpture under the instruction of Bertoldo di Giovanni and came to the attention of Lorenzo de’ Medici himself. Lorenzo de’ Medici (“Lorenzo the Magnificent”) invited the young Michelangelo to live in the Medici palace as a member of the household — not as a servant but as a protegé, eating at the family table and receiving the equivalent of a humanist education in the company of the Platonic Academy’s scholars (Angelo Poliziano, Marsilio Ficino, Giovanni Pico della Mirandola) and the Medici family itself.

Lorenzo de’ Medici died in April 1492. Michelangelo was 17 years old. With the collapse of the Medici patronage, he returned to his father’s house in Florence. Within a year, he had begun his illegal anatomical dissections.

NOT Lying Down: The Sonnet That Documents the Ceiling

The single most widely believed misconception about Michelangelo is that he painted the Sistine Chapel ceiling lying on his back. He did not. He painted it standing on a scaffold, with his neck bent back and his right arm raised above his head, working upward against gravity for four years. The specific documentary evidence: a sonnet Michelangelo wrote in approximately 1509–1510 to his friend Giovanni da Pistoia, in which he described his physical condition while painting the ceiling:

The sonnet (translated from the Italian, with some variation across translations): “I’ve grown a goitre by dwelling in this den — as cats from stagnant streams in Lombardy, or in what other land they hap to be — which drives the belly close beneath the chin. My beard turns up to heaven; my nape falls in, fixed on my spine; my breast-bone visibly grows like a harp; a rich embroidery bedews my face from brush-drops thick and thin. My loins into my paunch like levers grind; my buttock like a crupper bears my weight; my feet, unseen, are flung up in the air. My painting, dead from old, and dead in me, out of a rich man’s home a beggary: because my brush, above me all the time, drips down.”

The phrase “my brush, above me all the time, drips down” (“la mia pittura morta / difende ormai Giovanni e mio onore, / non sendo in loco buono, e io no pittore” in the original, but the upward-brush image is consistent across translations) directly documents the standing-with-arm-raised painting condition. The brush is above him because he is holding it above his own head, not because he is lying beneath it. The paint drips down onto his face because gravity acts downward on the paint from the brush he holds above himself, not because he is lying beneath a ceiling. The sonnet is the primary documentary refutation of the lying-down myth. See: Musei Vaticani — Sistine Chapel.

The Hidden Brain: JAMA October 1990

In the October 1990 issue of the Journal of the American Medical Association (JAMA), the physician and art enthusiast Frank Lynn Meshberger published an analysis of the Creation of Adam that proposed a specific and specific anatomical identification: the shape of God’s mantle (the swirling pink and grey drapery surrounding God and the angels in the upper portion of the composition) corresponds precisely to the shape of a human brain in sagittal cross-section (viewed from the side, the way an anatomist would section the brain for study).

Meshberger’s specific analysis: the outer contour of the mantle corresponds to the human brain’s outer cortical surface; the inner contour corresponds to the brain’s basal surface; the region where the angels cluster corresponds to the brain’s frontal lobe (the seat of complex cognitive processes and the imagination); the green scarf hanging below the mantle corresponds to the vertebral artery; and the foot-like protrusion in the lower right of the mantle corresponds to the brainstem. The correspondences are specific enough to be reproduced in textbooks: when the outline of God’s mantle is overlaid on a standard sagittal brain section, the match is immediately apparent.

The biographical interpretation: Michelangelo had been conducting illegal anatomical dissections since approximately 1493 (from the Santo Spirito monastery in Florence; see below). By 1508–1512, when he painted the Sistine Chapel ceiling, he had 15–19 years of anatomical study and was one of the most knowledgeable anatomists in Italy. The placement of the brain-shaped mantle in the Creation of Adam — specifically in the composition where God reaches outward to animate Adam — encodes the specific theological-anatomical proposition that the mind (the seat of the soul in the Neo-Platonic tradition) is the specific gift that God bestows on the human figure. The brain is present in God’s mantle at the moment of Adam’s animation. Meshberger’s identification in JAMA (1990) is the document that established this reading in the scholarly record. See: Creation of Adam: The JAMA Hidden Brain, 1990.

The 1.2 cm Gap: Why God and Adam Don’t Touch

In the Creation of Adam, the most recognisable compositional element is the gap between God’s extended right index finger and Adam’s extended left index finger. The fingers do not touch. The gap — which has been measured in reproductions and from the fresco itself at approximately 1.2 cm in the original — is the composition’s most deliberate and most specific event.

The gap’s specific significance: in the biblical narrative of Genesis, God creates Adam from the dust of the earth and breathes life into him (“And the LORD God formed man of the dust of the ground, and breathed into his nostrils the breath of life; and man became a living soul” — Genesis 2:7). The breath, not the touch, is the specific act of animation in the biblical text. Michelangelo’s compositional choice — to depict the moment immediately before or at the same instant as the divine animation, with the fingers not yet touching — encodes the specific quality of the potential rather than the actuality: the energy that crosses the gap without physical contact, the animation that occurs without touch. The gap is the specific compositional representation of the divine creative act’s quality: it is energy and breath, not physical contact.

The 1.2 cm gap has generated sustained scholarly discussion about the neurological and theological implications of Meshberger’s brain identification in the context of the gap: if the brain is present in God’s mantle, and the animation is transmitted across the gap without contact, then the animation is specifically mental or cognitive — the gift of the mind transmitted across the space between the divine and the human without physical touch. The gap and the brain are the same compositional programme: the Creation of Adam is the story of the gift of the mind, encoded simultaneously in a neuroanatomical shape and a non-contact transmission gap.

The Illegal Dissections: Santo Spirito Monastery, 1493

Beginning in approximately 1493, at approximately 18 years old, Michelangelo began conducting anatomical dissections of corpses at the Santo Spirito monastery in Florence. The dissections were illegal: the Catholic Church’s canon law prohibited the dissection of human remains, and civic law in most Italian cities imposed penalties for unauthorized dissection. Michelangelo gained access to the Santo Spirito monastery through a specific quid pro quo: he provided the monastery’s prior with a wooden crucifix (now in the Casa Buonarroti in Florence, confirmed as Michelangelo’s work by 20th-century attribution research) in exchange for access to the corpses that the monastery received from its attached hospital.

Michelangelo’s anatomical programme: he is documented to have dissected human corpses from approximately 1493 through the early 1500s, and possibly into the 1510s — the period that encompasses the Sistine Chapel ceiling (1508–1512). His anatomical knowledge, encoded in the figures’ musculature and skeletal structure across the ceiling and the Last Judgment (1536–1541), is the most specific documentary evidence of the dissections’ content: every muscular figure in the ceiling reflects the specific knowledge of a person who had examined human musculature directly, not from the conventional artistic stylization of the body’s external appearance but from the specific internal structure of muscle, fascia, bone, and nerve.

The Sistine Chapel Ceiling: Four Years, One Person

Pope Julius II commissioned the Sistine Chapel ceiling from Michelangelo in 1508. The commission was initially for a relatively modest programme: the twelve apostles in the spandrels above the windows, with decorative geometric patterns filling the rest of the vault. Michelangelo rejected this programme as “Povera cosa” (“a poor thing”) and proposed a vastly more ambitious replacement: the complete narrative of the Book of Genesis from the Creation to the Flood, with the Hebrew prophets and the pagan Sibyls alternating in the spandrels, and the ancestors of Christ in the arched lunettes above the windows. Julius II accepted the expanded programme.

Michelangelo executed the ceiling largely alone: he employed assistants for the rough plaster work and some of the preparatory stages, but the painting itself — the specific application of buon fresco (painting on wet plaster) across the vault’s 520 m² surface — was done primarily by his own hand. The ceiling required approximately 300 working days of fresco painting, spread over approximately four years (1508–1512), with interruptions for papal visits, diplomatic crises, and the specific logistical challenges of managing a scaffold system in the chapel’s live liturgical space. Michelangelo designed and built his own scaffold system — a flat platform suspended from the chapel’s walls at the level of the windows, not touching the floor, allowing the chapel to be used for its normal liturgical functions while the ceiling was being painted above.

The specific emotional programme of the four years: Michelangelo was, by his own account and by Vasari’s, deeply unhappy during the Sistine Chapel ceiling commission. He considered himself primarily a sculptor, not a painter; he resented the commission; he quarrelled repeatedly with Julius II; and he experienced the four-year ceiling project as an unwanted interruption of his primary work (the Julius II tomb commission, which had originally been the most ambitious project of his career and which he was forced to set aside for the ceiling). The ceiling was made, in Michelangelo’s own experience, under duress, in conditions of physical discomfort (the sonnet documents this), by a man who did not want to be there. The result is the most celebrated ceiling in Western art history. See: Musei Vaticani — Sistine Chapel.

The Last Judgment: Self-Portrait as the Flayed Skin

The Last Judgment (1536–1541) covers the entire altar wall of the Sistine Chapel — a 13.7 × 12.2 m fresco depicting Christ as judge at the centre, surrounded by the assembled saints and martyrs, with the righteous ascending to heaven at the left and the damned descending to hell at the right. It was commissioned by Pope Clement VII in 1533 and executed under Pope Paul III (who succeeded Clement after his death in 1534) between 1536 and 1541.

The most specific biographical element of the Last Judgment: in the lower right quadrant of the composition, among the ascending righteous, the apostle Saint Bartholomew holds a knife (the instrument of his martyrdom — he was flayed alive) and a piece of flayed human skin. The skin’s face — the face of the flayed skin that Bartholomew holds — is a likeness of Michelangelo himself. He placed his own face on the dead, flayed, stretched skin of the martyred apostle. The identification was first proposed in 1925 and has been confirmed by comparison with the portrait of Michelangelo in the Museo del Bargello in Florence and with other documented likenesses.

The specific biographical programme of the self-portrait as flayed skin: Michelangelo was 61 years old when he began the Last Judgment and 66 when he finished. He had survived multiple shifts in papal patronage (Julius II’s death, Leo X’s pontificate, Hadrian VI’s reign, Clement VII’s commission, Paul III’s commission); the Sack of Rome in 1527; the destruction of his primary patron family (the Medici’s expulsion from Florence); and the specific exhaustion of a career that had begun with the ceiling commission 28 years earlier. His self-portrait as the flayed skin that Bartholomew holds is the most specifically autobiographical statement in the Last Judgment: the painter who has been working for 28 years places himself as the dead, flayed, emptied skin among the martyrs. He is not ascending; he is not in the cloud of the righteous; he is held by the apostle who was also flayed, a skin without its body, the specific emblem of the exhausted artist who has been emptied by the work. See: Musei Vaticani — Sistine Chapel Last Judgment. View Last Judgment Triptych at DeckArts →

Michelangelo as Heraclitus in the School of Athens

In Raphael’s School of Athens (1509–1511, Stanza della Segnatura, Musei Vaticani), the centre-right foreground figure of Heraclitus — the pre-Socratic philosopher of perpetual change and flux — has Michelangelo’s face. Raphael added this figure after secretly entering the Sistine Chapel to view Michelangelo’s ceiling in progress, without Michelangelo’s knowledge or permission. The identification of Heraclitus’s face as Michelangelo’s has been confirmed by comparison with documented Michelangelo portraits and is universally accepted.

Raphael’s choice: Heraclitus — the philosopher who held that all things are in perpetual flux (“panta rhei,” “all things flow”), that the fundamental reality is fire, and that strife and opposition are the generative principles of existence — as the face of Michelangelo. The most solitary, most physically massive, most psychologically dark figure in the School of Athens is also the most specifically Michelangelo-appropriate philosophical identity: the painter of the Sistine Chapel ceiling as the philosopher of perpetual change, perpetual strife, and the fire that underlies all things. Michelangelo was reportedly displeased by the identification. See: Raphael: School of Athens Complete Guide.

Died Aged 88: The Longest Life in Renaissance Art

Michelangelo died on 18 February 1564 in Rome, aged 88 years and 348 days — the longest life of any major artist of the Italian Renaissance and one of the longest lives of any major European artist of any period before the 20th century. He outlived: Raphael by 44 years (Raphael died at 37); Leonardo da Vinci by 45 years (Leonardo died at 67); Botticelli by 54 years; his patron Lorenzo de’ Medici by 72 years. He lived long enough to see the emergence of Mannerism, the Counter-Reformation, the beginning of the Baroque tradition, and the first decades of the architectural programme he directed for Saint Peter’s Basilica (appointed architect of Saint Peter’s in 1547, at age 72; the basilica was not completed until after his death).

His last words, as reported by Vasari: he commended his soul to God, his body to the earth, and his goods to his nearest relatives. His servant Daniele da Volterra was present at his death. He was initially buried in the church of Santi Apostoli in Rome, but his body was subsequently removed secretly to Florence by his nephew Lionardo Buonarroti (at Michelangelo’s own expressed wish to be buried in Florence rather than Rome) and re-buried in the Basilica di Santa Croce in Florence on 14 March 1564 — the same church where his tomb remains today. See: Michelangelo: Creation of Adam Complete Guide.

Michelangelo for Home Decor

Michelangelo’s work in the DeckArts range is the most specifically anatomical and most specifically theological of any classical art available at DeckArts. The Creation of Adam single (~$140) and the Last Judgment triptych (~$310) are the two primary Michelangelo domestic installations:

Creation of Adam single (~$140) on warm white: The JAMA hidden brain (confirmed October 1990); the 1.2 cm gap (the specific deliberate non-touch); the illegal dissections from 1493; the scaffold system Michelangelo designed himself; the four years under duress. Above the home office desk at 125–145 cm (seated eye level): the most specifically anatomical and most specifically theological classical art for a person interested in the intersection of art, science, and the history of the body. The JAMA identification is the most specific discovery in Michelangelo’s biography: a physician, in 1990, 478 years after the ceiling was painted, identified the shape of the human brain in God’s mantle. View Creation of Adam at DeckArts →

Last Judgment triptych (~$310) on warm charcoal or forest green: The most specifically autobiographical and most psychologically extreme Michelangelo at DeckArts. Michelangelo’s own face on the flayed skin of Saint Bartholomew; the 66-year-old artist placing himself among the martyrs as an emptied skin. Above the primary living room sofa wall on warm charcoal: the most emotionally intense Michelangelo domestic primary. View Last Judgment Triptych at DeckArts →

Four Complete Michelangelo Programmes

Programme 1: The Anatomical Study Desk (~$140)
Warm white facing-desk wall + Creation of Adam single (~$140) at 125–145 cm (seated eye level) + directed 2700K warm LED art spot (separate dimmer). The JAMA hidden brain above the home office desk. “A physician identified the human brain in God’s mantle in October 1990, 478 years after the ceiling was painted. Michelangelo had been doing illegal dissections since 1493.” Total art: ~$140. Best for: physicians, scientists, medical students, art historians, anyone with a specific interest in the intersection of art and anatomy.

Programme 2: The Renaissance Primary Wall (~$450)
Warm white or warm charcoal primary sofa wall + Last Judgment triptych (~$310) at 155–165 cm (the self-portrait as flayed skin; the 66-year-old artist among the martyrs; the most emotionally extreme Michelangelo) + Creation of Adam single (~$140) on the adjacent study wall at 125–145 cm (the hidden brain; the 1.2 cm gap). Two Michelangelo biographical programmes in two rooms: the cosmic theological above the gathering space; the anatomical-theological above the working position. Total art: ~$450.

Programme 3: The Vatican Renaissance Triptych (~$590)
Warm white primary sofa wall + School of Athens triptych (~$310) at 155–165 cm (Raphael’s composition in which Michelangelo appears as Heraclitus; Plato is Leonardo; Julius II chose philosophers over apostles; Raphael died at 37) + Creation of Adam single (~$140) adjacent wall at 125–145 cm. Two simultaneous Vatican biographical programmes from the same physical building (the Apostolic Palace, Vatican), painted by two painters (Raphael 1509–1511; Michelangelo 1508–1512) who knew each other and whose work was influenced by each other. Total art: ~$450. See: Raphael: School of Athens.

Programme 4: The Renaissance Complete Living Room (~$730)
Warm white throughout + Last Judgment triptych (~$310) primary sofa wall + School of Athens triptych (~$310) secondary sofa wall or library primary + Creation of Adam single (~$140) facing the desk. Three simultaneous Renaissance biographical programmes from three completely different emotional and intellectual registers: the apocalyptic theological (Last Judgment; Michelangelo as flayed skin) + the philosophical humanist (School of Athens; Plato is Leonardo; Julius II chose philosophers) + the anatomical creative act (Creation of Adam; JAMA brain; 1.2 cm gap). Total art: ~$760.

FAQ

Did Michelangelo paint the Sistine Chapel ceiling lying on his back?

No. Michelangelo painted the Sistine Chapel ceiling standing on a scaffold with his neck bent back and his right arm raised above his head, working upward against gravity. The primary documentary evidence: a sonnet he wrote to his friend Giovanni da Pistoia in approximately 1509–1510, which describes his physical condition while painting the ceiling. The key phrase: “my brush, above me all the time, drips down” — the brush is above him because he is holding it above his own head (standing, painting upward), not because he is lying beneath it. The paint drips down onto his face from the brush he holds above himself. The sonnet also documents the specific physical discomforts of the standing-with-arm-raised position: his beard turns up to heaven; his nape falls in; his breast-bone grows like a harp. He did not lie down. See: Musei Vaticani — Sistine Chapel. DeckArts Creation of Adam single from ~$140.

What is the hidden brain in the Creation of Adam?

In the October 1990 issue of the Journal of the American Medical Association (JAMA), physician Frank Lynn Meshberger identified that the shape of God’s mantle (the swirling pink and grey drapery surrounding God and the angels) in the Creation of Adam corresponds precisely to the outline of a human brain in sagittal cross-section. The match is specific: the outer contour corresponds to the brain’s outer cortical surface; the region where the angels cluster corresponds to the frontal lobe; the green scarf below the mantle corresponds to the vertebral artery; the foot-like protrusion corresponds to the brainstem. Michelangelo had been conducting illegal anatomical dissections since approximately 1493 (from the Santo Spirito monastery in Florence) and was one of the most knowledgeable anatomists in Italy by 1508–1512. The identification was made 478 years after the ceiling was painted. See: Creation of Adam: JAMA 1990 Complete Guide. DeckArts Creation of Adam single from ~$140.

Where is Michelangelo buried?

In the Basilica di Santa Croce in Florence, Italy, in a tomb designed by Giorgio Vasari (his biographer). His body was originally buried in the church of Santi Apostoli in Rome on 18 February 1564, the day of his death. His nephew Lionardo Buonarroti subsequently removed the body secretly to Florence (at Michelangelo’s expressed wish) and it was re-buried in Santa Croce on 14 March 1564. The tomb in Santa Croce is in the right nave, near the tombs of Galileo and Machiavelli — Florence’s three most celebrated intellectual figures are buried within a few metres of each other. He died on 18 February 1564, aged 88, in Rome. DeckArts from ~$140. Musei Vaticani — Sistine Chapel.

Article Summary

Michelangelo Buonarroti (6 March 1475 – 18 February 1564, Caprese to Rome) is the most celebrated artist of the Italian Renaissance. Eight specific biographical facts that make him permanently inexhaustible: (1) NOT painted lying down — documented by his own 1509–1510 sonnet to Giovanni da Pistoia: “my brush, above me all the time, drips down”; (2) The hidden brain in God’s mantle in the Creation of Adam was identified by physician Frank Lynn Meshberger in JAMA October 1990 — 478 years after the ceiling was painted; (3) The 1.2 cm gap between God’s and Adam’s fingers is the deliberate non-touch: energy and animation without physical contact; (4) He conducted illegal anatomical dissections from the Santo Spirito monastery in Florence from approximately 1493 onward, in exchange for a wooden crucifix given to the prior; (5) The ceiling was painted under duress — Michelangelo considered himself primarily a sculptor, hated the commission, and quarrelled repeatedly with Julius II; (6) He placed his own face on the flayed skin of Saint Bartholomew in the Last Judgment (1536–1541): the 66-year-old artist as the emptied, dead skin held by the martyred apostle; (7) He appears in Raphael’s School of Athens as Heraclitus — the philosopher of perpetual flux and strife — added by Raphael after secretly entering the Sistine Chapel to view the ceiling in progress; (8) He died aged 88 — the longest life of any major Italian Renaissance artist, outliving Raphael by 44 years. DeckArts Creation of Adam single (~$140) and Last Judgment triptych (~$310). Ships from Berlin. 30-day return.

About the Author

Stanislav Arnautov is the founder of DeckArts and a creative director from Ukraine based in Berlin.

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